Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
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چکیده
منابع مشابه
Epigenetic boundaries of tumour suppressor gene promoters: the CTCF connection and its role in carcinogenesis
Genetic and epigenetic regulations are essential mechanisms that ensure proper early and subsequent mammalian programming of diverse cellular processes. These mechanisms affect transcriptional regulation, stem cell determination and cell cycle control, including senescence and aging. It is not surprising that perturbation of the exquisite balance between genetic and epigenetic regulation can le...
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ژورنال
عنوان ژورنال: Nature
سال: 2008
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature06468